A new producer of nucleocidin!

For over 60 years, only Streptomyces calvus was known to produce the fluorosugar nucleocidin. This is a problem, as S. calvus is a terrible producer of this valuable molecule (about 0.5 mg/L culture). Zechel lab PhD student Ola Pasternak and collaborators from the University of Freiburg have used a genome mining approach to find a new producer of this valuable molecule. This result sets the stage for finding better producers of nucleocidin and new derivatives. See our new paper in the Journal of Biotechnology describing this important milestone!


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